Endocrine Abstracts

Ghrelin is stored alongside glucagon in developing islet, although in a discrete cellular compartment, the pancreatic ε-cell. However, recent observations have shown a subpopulation of ghrelin/glucagon-double-positive cells in developing pancreas. The aim of the present study was to examine the developmental patterns of ghrelin- and glucagon-immunoreactive (ir) cells expression and possible co-localization of these hormones during human pancreas development. For this purp...